Pattern of serum concentrations of prolactin and progesterone during pregnancy and lactation in the brown hare (Lepus europaeus)

Autor: M. Caillol, A. S. McNeilly, M. Mondain-Monval
Rok vydání: 1990
Předmět:
Zdroj: Journal of Endocrinology. 124:11-17
ISSN: 1479-6805
0022-0795
DOI: 10.1677/joe.0.1240011
Popis: A heterologous radioimmunoassay system developed for the rabbit has been shown to measure prolactin in the hare. Concentrations of prolactin showed a significant (Ps.e.m.) μg/l; n= 10 and 9 respectively) in pregnant females isolated from males, as well as in pregnant females kept with males and mating prepartum. This rise of prolactin at the end of pregnancy was not due to mating stimuli and occurred at a time when progesterone levels were still high (159 nmol/l). The injection of a slow-release preparation of bromocriptine (5 mg s.c.), which reduces prolactin secretion at the end of pregnancy, did not impair parturition. During lactation, prolactin levels increased significantly (61·2±19·8 compared with 5·3 ± 0·1 μg/l; P Journal of Endocrinology (1990) 124, 11–17
Databáze: OpenAIRE