Characteristics and Determinants of Pulse Pressure-Age Relationship in Healthy and Non-treated Hypertensive Subjects of Argentinean Population
| Autor: | Ariel Pascaner, Alejandro Diaz, Sandra Wray, Edmundo I. Cabrera Fischer |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Mean arterial pressure Multivariate analysis Population Blood Pressure Pulse Wave Analysis Vascular Stiffness Framingham Heart Study Internal medicine Internal Medicine medicine Humans Arterial Pressure education Pulse wave velocity education.field_of_study business.industry Middle Aged medicine.disease Pulse pressure Ageing Hypertension Cardiology Arterial stiffness business |
| Zdroj: | Current Hypertension Reviews. 17:137-148 |
| ISSN: | 1573-4021 |
| DOI: | 10.2174/1573402116999201210195123 |
| Popis: | Background: The relationship between the increases in pulse pressure (PP) and arterial stiffness determined by aging or systemic hypertension has been widely reported. These findings are supported by large-cohort analyzes conducted in well-known populations, such as Framingham Study. However, there is evidence that an age-PP curvilinear relationship may exist in hypertensive subjects. This study aimed to evaluate the age-related change in pulse pressure and arterial stiffness in a population-based study. Methods: Carotid-femoral Pulse Wave Velocity (cfPWV) were obtained in 2075 subjects. Results: Age-related changes of PP showed a curvilinear relationship (R=0.39, p Conclusion: In conclusion, age-related changes in PP showed a curvilinear relationship and no parallelism with the age-cfPWV relationship for both normotensive and hypertensive subjects. The determinants of PP impact it differently depending on age and the pathological condition of the subject. |
| Databáze: | OpenAIRE |
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