A randomised controlled trial on effectiveness and feasibility of sport climbing in Parkinson’s disease
| Autor: | Dominik Roth, Marco Treven, Peter Dabnichki, Laurenz Wizany, Ulrike Willinger, Sarah Zimmel, Anna Flotz, Lucia Gassner, Michaela Schmoeger, Jakob Gruber, Sebastian Hasenauer, Heidemarie Zach, Agnes Langer, Walter Maetzler, Rochus Pokan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
030506 rehabilitation
medicine.medical_specialty Parkinson's disease Class iii Article law.invention Part iii 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Primary outcome Randomized controlled trial law Rating scale medicine RC346-429 Adverse effect business.industry Rehabilitation medicine.disease Neurology Outcomes research Climbing Physical therapy Basal ganglia Neurology. Diseases of the nervous system Neurology (clinical) 0305 other medical science business human activities 030217 neurology & neurosurgery |
| Zdroj: | NPJ Parkinson's Disease npj Parkinson's Disease, Vol 7, Iss 1, Pp 1-9 (2021) |
| Popis: | Physical activity is of prime importance in non-pharmacological Parkinson’s disease (PD) treatment. The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. A total of 48 PD patients without experience in climbing (average age 64 ± 8 years, Hoehn & Yahr stage 2–3) were assigned either to participate in a 12-week sport climbing course (SC) or to attend an unsupervised physical training group (UT). The primary outcome was the improvement of symptoms on the Movement Disorder Society-Sponsored Revision of the Unified Parkinson’s Disease Rating Scale part III (MDS-UPDRS-III). Sport climbing was associated with a significant reduction of the MDS-UPDRS-III (−12.9 points; 95% CI −15.9 to −9.8), while no significant improvement was to be found in the UT (−3.0 points; 95% CI −6.0 to 0.1). Bradykinesia, rigidity and tremor subscales significantly improved in SC, but not in the unsupervised control group. In terms of feasibility, the study showed a 99% adherence of participants to climbing sessions and a drop-out rate of only 8%. No adverse events occurred. This trial provides class III evidence that sport climbing is highly effective and feasible in mildly to moderately affected PD patients. |
| Databáze: | OpenAIRE |
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