Twice-daily application of topical corticosteroids with a squirt system for patients with steroid-responsive olfactory impairment

Autor:	Chih-Hung Shu, Dai-Lou Lin, Yun-Ting Chao
Rok vydání:	2016
Předmět:	Adult Male medicine.medical_specialty Triamcinolone acetonide Visual analogue scale medicine.drug_class medicine.medical_treatment Triamcinolone Acetonide 03 medical and health sciences Olfaction Disorders 0302 clinical medicine medicine Humans 030223 otorhinolaryngology Glucocorticoids Aged Retrospective Studies Aged 80 and over business.industry Retrospective cohort study General Medicine Middle Aged Steroid responsive Surgery Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Anesthesia Oral steroid Corticosteroid Female OLFACTORY IMPAIRMENT business Topical steroid medicine.drug
Zdroj:	Acta oto-laryngologica. 136(12)
ISSN:	1651-2251
Popis:	Twice-daily topical corticosteroid treatment using a squirt system was beneficial in maintaining improvements in olfactory dysfunction which had been achieved by oral steroid treatment.Some patients suffering from olfactory dysfunction respond well to corticosteroids. However, maintaining these improvements is challenging. The aim of this study was to evaluate the maintenance effect of twice-daily topical steroid treatment using a squirt system.Twenty-two anosmic patients with an increase in odor threshold, discrimination, and identification (TDI) scores in Sniffin' Sticks tests by more than six points after 1-week of oral steroid treatment were enrolled. All the patients used a squirt system to apply topical corticosteroids and were followed up at 1, 3, and 6 months.Nineteen, 16, and 10 patients were followed-up at 1, 3, and 6 months after treatment, respectively. All the patients had significant visual analog scale scores improvements compared to pre-treatment. The mean improvements in TDI scores were 9.80 (p 0.001), 11.58 (p = 0.001), and 13.87 (p = 0.005) after 1, 3, and 6 months of treatment, respectively. The self-rated and objective olfactory function scores were maintained with steroid squirt therapy without significant decline, even in the patients who were followed up for 6 months.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33de235fd6b03fe2d6d458f817990518 https://pubmed.ncbi.nlm.nih.gov/27468143 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.