SARS-CoV-2 Seropositivity in Asymptomatic Frontline Health Workers in Ibadan, Nigeria
| Autor: | Fabian Edem, Jude Nwaokenye, Nnaemeka Awah, Gabriel Odok, Bola Eseile, Olabisi Bamidele, Abimbola Amoo, Gabriel Oluwole, Chioma Udeh, Olatunde Olayanju |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Health Personnel 030231 tropical medicine Population Nigeria Antibodies Viral Asymptomatic 03 medical and health sciences Young Adult 0302 clinical medicine Seroepidemiologic Studies Virology Environmental health Pandemic Global health Medicine Seroprevalence Humans 030212 general & internal medicine Health Workforce Young adult education education.field_of_study business.industry SARS-CoV-2 COVID-19 Articles Middle Aged Personnel Hospital Infectious Diseases Immunoglobulin G Parasitology Female medicine.symptom business |
| Zdroj: | The American Journal of Tropical Medicine and Hygiene |
| ISSN: | 1476-1645 0002-9637 |
| Popis: | Global health has been thrown into turmoil by the COVID-19 pandemic, which has caused devastating morbidity and unprecedented loss of life in almost all continents of the world. It was predicted that the magnitude of the pandemic in Africa will be high because of poor health structure and intensely poor living condition, but that has not happened, surprisingly. It was hypothesized that the youthful population and a vastly primed immune system were protective, and many people may have been exposed without coming down with the severe disease. Most of them would have presented in hospitals with other medical conditions and possibly transmit COVID-19 to health workers inadvertently. This study is designed to measure serum SARS-CoV-2 IgG levels in health workers as a marker of latent exposure. Asymptomatic frontline health workers were randomly selected from the University College Hospital Ibadan, Nigeria; venous blood samples were obtained from them, and the serum SARS-CoV-2 IgG level was determined using ELISA techniques. A proportion of participants with seropositivity were obtained, and factors associated with seropositivity were determined. A total of 133 participants were recruited for this study, and 60 (45.1%) of them were seropositive for SARS-CoV-2. Among the seropositive participants were doctors, nurses, health assistants, laboratory scientists and technicians, and nonmedical staff. Obstetrics, gynecology, and emergency departments had higher odds of seropositivity. Seroprevalence of SARS-CoV-2 is very high among frontline health workers, though asymptomatic. This calls for a more stringent precaution against further spread within the hospital environment. |
| Databáze: | OpenAIRE |
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