Proinflammatory versus anti-inflammatory response in sepsis patients: looking at the cytokines
| Autor: | Sabari Das, Ashish Garg, Sumit Ray, L Mohan Srivastava, Dimple Anand, Seema Bhargava, Debashish Dhar, Saurabh Taneja |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
0303 health sciences
business.industry Mortality rate Human study Inflammation 030204 cardiovascular system & hematology Bioinformatics medicine.disease Critical Care and Intensive Care Medicine 3. Good health Proinflammatory cytokine Sepsis 03 medical and health sciences 0302 clinical medicine Immune system Anti-inflammatory response Poster Presentation Immunology Medicine medicine.symptom business 030304 developmental biology |
| Zdroj: | Critical Care |
| ISSN: | 1364-8535 |
| DOI: | 10.1186/cc14016 |
| Popis: | Despite improvements in supportive care, mortality rates in sepsis remain substantially high. Sepsis exhibits phases of enhanced inflammation, alternating with immune suppression with a resultant variant time point of mortality; yet no human study has correlated levels of cytokines to the timeline of mortality. Our study attempts to analyze the association of levels of proinflammatory and anti-inflammatory cytokines in sepsis with the timeline of death in terms of early ( 5 days) mortality, and day of death. We also assessed correlation of these cytokines with length of stay. |
| Databáze: | OpenAIRE |
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