Comparative analysis of progesterone and placental protein 14 measurements in the evaluation of luteal function
| Autor: | Marcelo C. Batista, George R. Merriam, Tannia P. Cartledge, Ann W. Zellmer, Lynnette K. Nieman, Nicola Bravo, D. Lynn Loriaux |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors media_common.quotation_subject Diagnostic accuracy Serum progesterone Luteal Phase Pregnancy Proteins Luteal phase Endometrium Internal medicine medicine Humans Progesterone Menstrual cycle Glycoproteins media_common business.industry Obstetrics and Gynecology Placental protein Middle Aged medicine.anatomical_structure Endocrinology Glycodelin Female business Luteinizing hormone Function (biology) |
| Zdroj: | American Journal of Obstetrics and Gynecology. 168:1522-1527 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/s0002-9378(11)90793-5 |
| Popis: | Our purpose was to investigate the diagnostic accuracy of single or summed measurements of progesterone and placental protein 14, a progestin-dependent endometrial glycoprotein, in the evaluation of luteal function.Forty-five healthy women had daily blood measurements of luteinizing hormone, progesterone, and placental protein 14 during one menstrual cycle.Thirty-nine women had normal and six had deficient luteal function on the basis of serial progesterone determinations. Luteal insufficiency was not accurately diagnosed by single progesterone or placental protein 14 values or by integrated placental protein 14 measurements. In contrast, the condition was correctly identified in all but one cycle when the sum of progesterone on days 4 and 7 was49 nmol/L (15.4 ng/ml). A poor correlation was found between peak or integrated measurements of progesterone and placental protein 14.Measurement of serum progesterone, but not placental protein 14, on 2 days of the midluteal phase provides a convenient and reliable test of luteal function. |
| Databáze: | OpenAIRE |
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