Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment
| Autor: | Christian Gingert, Elisa Fattorini, Marco Dominietto, Simone E. Hieber, Vanessa Leung, Bekim Osmani, Tobia Brusa, Bert Müller, Philippe Büchler, Franc H. Hetzer |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty 0206 medical engineering Biomedical Engineering Adult population Anal Canal Biomimetic design 610 Medicine & health 02 engineering and technology Biology Prosthesis Design Article Artificial sphincter Maintaining continence Physical medicine and rehabilitation Biomimetic Materials medicine Humans Fecal incontinence Artificial fecal sphincter 620 Engineering 021001 nanoscience & nanotechnology 020601 biomedical engineering Prosthesis Failure Surgery medicine.anatomical_structure Fecal sphincter 570 Life sciences biology Sphincter Artificial muscle Electro-active polymer actuator Artificial Organs medicine.symptom 0210 nano-technology Fecal Incontinence |
| Zdroj: | Annals of Biomedical Engineering Fattorini, Elisa; Brusa, Tobia; Gingert, Christian; Hieber, Simone E; Leung, Vanessa; Osmani, Bekim; Dominietto, Marco D; Büchler, Philippe; Hetzer, Franc; Müller, Bert (2016). Artificial Muscle Devices: Innovations and Prospects for Fecal Incontinence Treatment. Annals of biomedical engineering, 44(5), pp. 1355-1369. Springer 10.1007/s10439-016-1572-z |
| ISSN: | 1573-9686 0090-6964 |
| Popis: | Fecal incontinence describes the involuntary loss of bowel content, which is responsible for stigmatization and social exclusion. It affects about 45% of retirement home residents and overall more than 12% of the adult population. Severe fecal incontinence can be treated by the implantation of an artificial sphincter. Currently available implants, however, are not part of everyday surgery due to long-term re-operation rates of 95% and definitive explantation rates of 40%. Such figures suggest that the implants fail to reproduce the capabilities of the natural sphincter. This article reviews the artificial sphincters on the market and under development, presents their physical principles of operation and critically analyzes their performance. We highlight the geometrical and mechanical parameters crucial for the design of an artificial fecal sphincter and propose more advanced mechanisms of action for a biomimetic device with sensory feedback. Dielectric electro-active polymer actuators are especially attractive because of their versatility, response time, reaction forces, and energy consumption. The availability of such technology will enable fast pressure adaption comparable to the natural feedback mechanism, so that tissue atrophy and erosion can be avoided while maintaining continence during daily activities. |
| Databáze: | OpenAIRE |
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