Parkinsonian signs are a risk factor for falls
| Autor: | Chinwe Nwadiogbu, Whitney Fitts, Jason Karlawish, Nabila Dahodwala, Helen L. Partridge |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Longitudinal study Time Factors Biophysics Neurological examination Risk Assessment Article Executive Function 03 medical and health sciences Cognition 0302 clinical medicine Parkinsonian Disorders Risk Factors medicine Humans Dementia Orthopedics and Sports Medicine 030212 general & internal medicine Risk factor Gait Stroke Depression (differential diagnoses) Aged Retrospective Studies Aged 80 and over Neurologic Examination medicine.diagnostic_test business.industry Incidence Rehabilitation Middle Aged Pennsylvania medicine.disease nervous system diseases Survival Rate Physical therapy Accidental Falls Female business 030217 neurology & neurosurgery Follow-Up Studies Cohort study Fall prevention |
| Zdroj: | Gait & Posture. 55:1-5 |
| ISSN: | 0966-6362 |
| Popis: | Background Parkinsonian signs are common, non-specific findings in older adults and associated with increased rates of dementia and mortality. It is important to understand which motor outcomes are associated with parkinsonian signs. Objectives To determine the role of parkinsonian signs on fall rates among older adults. Methods We conducted a longitudinal study of primary care patients from the University of Pennsylvania Health System. Adults over 55 years were assessed at baseline through surveys and a neurological examination. We recorded falls over the following 2 years. Parkinsonian signs were defined as the presence of 2 of 4 cardinal signs. Incident falls were compared between subjects with and without parkinsonian signs, and modified Poisson regression used to adjust for potential confounders in the relationship between parkinsonian signs and falls. Results 982 subjects with a mean age of 68 (s.d. 8.8) years participated. 29% of participants fell and 12% exhibited parkinsonian signs at baseline. The unadjusted RR for falls among individuals with parkinsonian signs was 1.36 (95% CI 1.05–1.76, p = 0.02). After adjusting for age, cognitive function, urinary incontinence, depression, diabetes, stroke and arthritis, individuals with parkinsonian signs were still 38% more likely to fall than those without parkinsonian signs (RR 1.38, 95% CI 1.04–1.82; p = 0.03). Falls among those with parkinsonian signs were more likely to lead to injury (53% vs 37%; p = 0.04). Conclusions Parkinsonian signs are a significant, independent risk factor for falls. Early detection of this clinical state is important in order to implement fall prevention programs among primary care patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect