Quality of Life After Caustic Ingestion
Autor: | Helene Corte, Emile Sarfati, Matthieu Faron, Mircea Chirica, Tigran Poghosyan, Thibault Voron, Pierre Cattan, Matthieu Bruzzi |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male medicine.medical_specialty Caustics Poison control Suicide Attempted Anxiety Hospital Anxiety and Depression Scale 03 medical and health sciences Esophagus 0302 clinical medicine Quality of life Internal medicine Burns Chemical Injury prevention medicine Humans In patient Caustic ingestion Depression (differential diagnoses) Retrospective Studies Depression business.industry humanities 030220 oncology & carcinogenesis Quality of Life Female 030211 gastroenterology & hepatology Surgery medicine.symptom business |
Zdroj: | Annals of Surgery. 274:e529-e534 |
ISSN: | 1528-1140 0003-4932 |
Popis: | OBJECTIVE The aim of the study was to evaluate long-term QOL after caustic ingestion. BACKGROUND Caustic ingestion strongly affects patient's QOL but data on the topic is scarce in the literature. METHODS QOL evaluation was conducted in survivors from a large cohort of patients with caustic injuries. QOL was assessed using the EORTC QLQ-OG25 module, the SF12v2 score, and the hospital anxiety and depression scale questionnaire. One hundred thirty-four patients (59 men, median age 43) completed the survey; 72 (54%) patients underwent emergency digestive resection and in 99 (74%) patients underwent esophageal reconstruction. Results of QOL questionnaires were compared to average values determined in healthy volunteers and in patients with esophageal cancers. RESULTS The median QLQ-OG25 score was 44 (34, 62) and values were significantly lower when compared to a normal population (P < 0.0001). SF12v2 scores were significantly inferior to those expected in a normal population on both the physical component summary (PCS) (43.3 ± 10.8; P < 0.0001) and the mental component summary (44 ± 9.7; P < 0.0001) scales. Emergency esophageal resection was significantly associated with higher QLQ-OG25 scores (P < 0.0001), but not with mental component summary (P = 0.3), PCS (P = 0.76), HAD anxiety (P = 0.95), and HAD depression scores (P = 0.59); results were similar after extended emergency resection. When compared to esophagocoloplasty alone, pharyngeal reconstruction had a significant negative impact on QLQ-OG25 (P < 0.0001), PCS (P = 0.01), and HAD depression (P = 0.0008) scores. CONCLUSIONS QOL is significantly impaired after caustic ingestion. QOL issues should not influence the emergency surgical strategy but deserve discussion before esophageal reconstruction for caustic injuries. |
Databáze: | OpenAIRE |
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