| Autor: |
Hiroaki Ueno, Yui Yano, Naoki Haraguchi, Tomomi Shiiya, Emi Ebihara, Eri Sumoto, Miyo Nakamura, Keiko Sasaba, Taisuke Uchida, Masamitsu Nakazato, Tomoho Noda, Emiko Kita, Tomoko Nobe, Akemi Umemura, Mayumi Azuma, Yudai Uehira, Naho Uchimura |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Journal of the American Nutrition Association. |
| ISSN: |
2769-707X |
| Popis: |
OBJECTIVE Konjac is a food mainly consumed in Asian countries with high fiber and low energy. Although glucomannan, a component of konjac, have been used for several clinical studies, there is few reports using konjac itself. This study examined the effects of the active consumption of konjac in patients with type 2 diabetes mellitus (T2DM). METHODS The study included 26 Japanese patients with T2DM. Participants were recommended to take konjac at least once a day using free konjac products (various noodles, rice, and desserts) and plate konjac for 12 weeks. RESULTS HbA1c and fasting plasma glucose levels significantly decreased from 8.3 ± 0.9% to 8.0 ± 0.8% and from 173.2 ± 44.4 to 152.8 ± 36.7 mg/dL, respectively. No significant changes were observed in body weight and insulin resistance indices, but the index for insulin secretion significantly increased. Serum high molecular weight adiponectin levels significantly increased. Plasma ghrelin, leptin and glucagon-like peptide-1 levels tended to decrease (p = 0.084), decrease (p = 0.057) and increase (p = 0.071), respectively. Actual konjac intake positively correlated with age (r = 0.61, p = 0.001). Body weight and HbA1c significantly decreased in patients aged ≥50 years than in those aged |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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