Risk Factors for Inspiratory Muscle Weakness in Chronic Heart Failure
| Autor: | Janaína Proença de Oliveira-Maul, Mariana Abreu Diz, Tatiana Satie Kawauchi, Naomi Kondo Nakagawa, Iracema Ioco Kikuchi Umeda, Lawrence P. Cahalin, Geisa Nascimento de Andrade, Julio Yoshio Takada, Fernanda Murata Murakami, Juliana Nascimento, Antonio de Pádua Mansur, Newton Nunes |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Weakness medicine.medical_specialty Blood Pressure Critical Care and Intensive Care Medicine Ventricular Function Left Pulmonary function testing 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Tobacco Smoking medicine Humans Muscle Strength Exercise Aged Heart Failure Muscle Weakness Ejection fraction business.industry Stroke Volume General Medicine Middle Aged medicine.disease Brain natriuretic peptide Pulmonary hypertension Respiratory Muscles Cross-Sectional Studies Blood pressure 030228 respiratory system Heart failure Chronic Disease Cardiology Female medicine.symptom business Body mass index |
| Zdroj: | Respiratory Care. 65:507-516 |
| ISSN: | 1943-3654 0020-1324 |
| Popis: | BACKGROUND: Chronic heart failure is commonly associated with inspiratory muscle weakness. However, few studies have investigated the risk factors for inspiratory muscle weakness in individuals with chronic heart failure and systolic dysfunction (left-ventricular ejection fraction [LVEF] METHODS: Seventy subjects were recruited in a cardiac center. We assessed clinical parameters, smoking history, peripheral muscle strength, pulmonary function, echocardiographic variables, and brain natriuretic peptide. The subjects were classified with inspiratory muscle weakness when the maximum inspiratory pressure was RESULTS: Thirty-six subjects (51%) had inspiratory muscle weakness. The subjects with inspiratory muscle weakness and the subjects with no inspiratory muscle weakness were similar in age, sex, body mass index, medication use, and physical activity. However, the subjects with inspiratory muscle weakness had lower LVEF (P = .003), systolic blood pressure (P = .01), diastolic blood pressure (P = .042), quadriceps muscle strength (P = .02), lung function (P = .035), increased brain natriuretic peptide (P = .02), smoking history (P = .01), and pulmonary hypertension incidence (P = .03). Multivariate logistic regression analysis found a lower LVEF, increased smoking history, and lower systolic blood pressure as significant independent predictors for inspiratory muscle weakness. CONCLUSIONS: The combination of lower LVEF, lower systolic blood pressure, and smoking history predicted inspiratory muscle weakness. Patients with suspected inspiratory muscle weakness should be examined and, if inspiratory muscle weakness exists, then inspiratory muscle training should be provided. Reducing inspiratory muscle weakness has the potential to improve many of the deleterious effects of chronic heart failure. |
| Databáze: | OpenAIRE |
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