Phenotypic mixing between reticuloendotheliosis virus and avian sarcoma viruses
| Autor: | Richard L. Witter, Lyman B. Crittenden, Peter K. Vogt, J.Lloyd Spencer, W. Okazaki |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Antiserum
Reticuloendotheliosis virus animal structures viruses Genetic Complementation Test Avian sarcoma Phenotype mixing Avian leukosis Biology medicine.disease Avian sarcoma virus Virology Alpharetrovirus Virus Cell Line Phenotype Retroviridae Avian Sarcoma Viruses Neutralization Tests Viral Interference Coinfection medicine Hexadimethrine Bromide |
| Zdroj: | Virology. 80:127-135 |
| ISSN: | 0042-6822 |
| Popis: | Coinfection of chicken embryo fibroblasts with reticuloendotheliosis virus (REV) and avian sarcoma virus leads to the formation of avian sarcoma viral pseudotypes which carry envelope determinants of REV. These pseudotypes can be neutralized by REV antiserum, have a host range which is different from that of any known avian sarcoma virus, and are unable to form foci in cells preinfected with REV. The REV stocks used in these experiments were plaque-purified. They were free of avian leukosis virus detectable in the COFAL tests, and their ability to form pseudotypes with avian sarcoma virus was neutralized with specific REV antiserum. |
| Databáze: | OpenAIRE |
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