Association of cholesterol and lifestyle markers with type 1 diabetes incidence rates at a population level
| Autor: | Sandro Vella, Maureen Bezzina Sultana, Stephen Fava |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty endocrine system diseases Adolescent Population Prevalence 030209 endocrinology & metabolism Blood Pressure Type 2 diabetes 030204 cardiovascular system & hematology Body Mass Index 03 medical and health sciences 0302 clinical medicine Sex Factors Internal medicine Diabetes mellitus medicine Humans education Child Life Style Type 1 diabetes education.field_of_study business.industry Incidence (epidemiology) Incidence Public Health Environmental and Occupational Health nutritional and metabolic diseases General Medicine medicine.disease Blood pressure Endocrinology Cholesterol Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Female business Body mass index Biomarkers Demography |
| Zdroj: | Journal of public health (Oxford, England). 39(3) |
| ISSN: | 1741-3850 |
| Popis: | Background We investigated the hypotheses that mean population body mass index (BMI), systolic blood pressure (SBP), fasting plasma glucose (FPG), total cholesterol (TC) and the prevalence of type 2 diabetes (T2DM) are correlated with type 1 diabetes (T1DM) incidence rates. Methods Population-based mean incidence rates for T1DM in children aged ≤14 years participating in the World Health Organization Diabetes Mondial (DiaMond) project were compared with population mean values for BMI, SBP, TC and FPG, as well as prevalence rates for T2DM as reported by The Global Burden of Metabolic Risk Factors Chronic Diseases Collaborating Group, using Spearman's rank correlation and multiple regression analysis. Results The mean incidence rate for T1DM in boys was significantly correlated with country mean BMI, SBP and TC in men and mean TC in women, and negatively correlated with the country incidence of T2DM in either gender. We also found significant correlations between mean incidence rates of T1DM in girls and mean BMI, SBP and TC in men and mean TC in women. In multiple regression analyses, mean TC emerged as the sole significant predictor for T1DM in both boys (P |
| Databáze: | OpenAIRE |
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