Acute Encephalopathy Associated with Influenza A Infection in Adults
| Autor: | Nelson Lee, Frederick G. Hayden, Niklas Lindegardh, Ka Shing Wong, David S.C. Hui, Chun-Kwok Wong, Paul K.S. Chan, Edward H.C. Wong, Joseph J.Y. Sung, Clive S. Cockram, Nicholas J. White |
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| Rok vydání: | 2010 |
| Předmět: |
Male
Microbiology (medical) Epidemiology Encephalopathy lcsh:Medicine Influenza A virus medicine.disease_cause Virus lcsh:Infectious and parasitic diseases Pathogenesis Cerebrospinal fluid Immunopathology Influenza Human Blood plasma cytokine adults medicine Influenza A virus Humans lcsh:RC109-216 Encephalitis Viral Aged Aged 80 and over business.industry lcsh:R Dispatch encephalopathy medicine.disease infection Infectious Diseases Immunology Cytokines Female influenza business Encephalitis |
| Zdroj: | Emerging Infectious Diseases Emerging Infectious Diseases, Vol 16, Iss 1, Pp 139-142 (2010) |
| ISSN: | 1080-6059 1080-6040 |
| DOI: | 10.3201/eid1601.090007 |
| Popis: | We report acute encephalopathy associated with influenza A infection in 3 adults. We detected high cerebrospinal fluid (CSF) and plasma concentrations of CXCL8/IL-8 and CCL2/MCP-1 (CSF/plasma ratios > or =3), and interleukin-6, CXCL10/IP-10, but no evidence of viral neuroinvasion. Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis. |
| Databáze: | OpenAIRE |
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