Lack of association between mitochondrial DNA polymorphisms and didexoxynucleoside-induced hyperlactataemia in black-African, HIV-1-infected patients
| Autor: | Ian Weller, Lilanganee Telisinghe, Martine Bolhaar, Alan Karstaedt, Salome Charalambous, Alison D. Grant, Alejandro Arenas-Pinto, Catherine J. E. Ingram, Neil Bradman, Rosemary Ekong |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Mitochondrial DNA business.industry Haplogroup H Public health Public Health Environmental and Occupational Health Single-nucleotide polymorphism medicine.disease Bioinformatics Virology Mitochondrial toxicity Infectious Diseases Pharmacotherapy Acquired immunodeficiency syndrome (AIDS) Poster Presentation medicine business Lipoatrophy health care economics and organizations |
| Zdroj: | Journal of the International AIDS Society Europe PubMed Central |
| ISSN: | 1758-2652 |
| Popis: | Background: Recent studies have shown some association between specific mitochondrial DNA (mtDNA) polymorphisms and peripheral neuropathy in both white European and black American populations. An association between mtDNA haplogroup H and peripheral lipoatrophy has been reported in white Europeans. Our group has shown a lack of association between mtDNA polymorphisms and the occurrence of HL in white Europeans exposed to dideoxynucleosides, but there have been no studies in black African people. Supplement: Abstracts of the Tenth International Congress on Drug Therapy in HIV Infection http://www.biomedcentral.com/content/pdf/1758-2652-13-S4-info.pdf Conference: Tenth International Congress on Drug Therapy in HIV Infection 7-11 November 2010 Glasgow, UK (Published: 8 November 2010) doi:10.1186/1758-2652-13-S4-P96 Cite this article as: Arenas-Pinto et al.: Lack of association between mitochondrial DNA polymorphisms and didexoxynucleoside-induced hyperlactataemia in black-African, HIV-1-infected patients. Journal of the International AIDS Society 2010 13(Suppl 4):P96. Full text: PubMed Central: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113104/ |
| Databáze: | OpenAIRE |
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