[A case of agranulocytosis and jaundice due to cellulitis caused by insect bite]
| Autor: | Yoshikazu Ohbayashi, Shinichi Shimizu, Shigeki Kuribayashi, Masataka Ohnishi, Tomoyuki Yahata, Shomei Sha, Yozo Matsuda, Ryosuke Yoshihara, Kimimaro Hanakawa |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
Jaundice medicine.disease_cause Serology Lesion medicine Humans Right Thigh High grade fever business.industry Insect Bites and Stings Cellulitis General Medicine Middle Aged medicine.disease Dermatology Surgery Staphylococcus aureus Female medicine.symptom business Piperacillin medicine.drug Agranulocytosis |
| Zdroj: | Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 65(1) |
| ISSN: | 0387-5911 |
| Popis: | A 58-year-old female was introduced to our hospital for admission on April 22, 1988, because of high grade fever and agranulocytosis. She had eschers on her left zygomatic region and medial region of the right thigh. The latter lesion was accompanied by cellulitis. Laboratory tests showed her WBC was 600/mm3 and T-Bil was 6.51 mg/dl. By using minocyclin, piperacillin and other drugs, her general condition and laboratory data became better in a few days. Although her skin lesions resembled "Tsutsugamushi disease", serological tests showed no evidence for Rickettia infection. So we could not rule out that another kind of insect bite may also develop such a severe clinical course. Furthermore, Staphylococcus aureus or Clostridium spp., which were detected in her pus, might have the toxic effects of inducing agranulocytosis, which might mainly be the result from the local WBC emigration, and jaundice, just like the effects of the endotoxin of Gram negative bacteria. |
| Databáze: | OpenAIRE |
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