Neuropsychological and executive screening in obstructive sleep apnea: early effect of ventilatory therapy
Autor: | Marina Maffoni, Antonia Pierobon, Eugenia Taurino, Rita Maestroni, Martina Vigorè, Valeria Torlaschi, Roberto Maestri, Francesco Fanfulla |
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Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Neuropsychological Tests Hospital Anxiety and Depression Scale Psychosocial Intervention Positive-Pressure Respiration 03 medical and health sciences 0302 clinical medicine Quality of life medicine Humans Cognitive Dysfunction Aged Sleep Apnea Obstructive business.industry Neuropsychology Montreal Cognitive Assessment General Medicine Middle Aged medicine.disease Executive functions Obstructive sleep apnea Distress 030220 oncology & carcinogenesis Physical therapy Quality of Life 030211 gastroenterology & hepatology Female Verbal memory business |
Zdroj: | Minerva medica. 112(3) |
ISSN: | 1827-1669 |
Popis: | Background Obstructive sleep apnea (OSA) is often associated with clinical, psychological and neuropsychological comorbidities such as Mild Cognitive Impairment (MCI). This study evaluated changes in clinical, psychosocial, Health Related Quality of Life (HRQoL) and neuropsychological profile in OSA subjects after ventilatory therapy, making comparison with normative data. The aim of the study was to verify the suitability of the HRQoL and neuropsychological screening tests in detecting variations in OSA subjects. Methods At baseline, 32 OSA subjects underwent the following assessment: EuroQol (EQ-5D-3L) and EQ VAS, Hospital Anxiety and Depression Scale (HADS), Montreal Cognitive Assessment (MoCA) and Frontal Assessment Battery (FAB). After the ventilatory titration, 31 OSA subjects repeated the EQ VAS, MoCA and FAB assessment. Results The analyzed subjects (77% male, 58.97±10.06 years old and 47.34±26.67 AHI [ev*hr-1]) showed low emotive distress, a lower perception of HRQoL than normative data and 35.48% of them exhibited executive deficits, too. MCI was detected in 3.2% and 48.4% of subjects after normative Italian and international correction, respectively. Subsequently the ventilatory therapy and the rehabilitative interdisciplinary treatment, subjects improved in EQ VAS (68.23±18.73 vs. 87.13±10.80, P=0.0001), FAB scores (15,30±2.03 vs. 16,65±1,40, P=0.007) and MoCA memory subtest scores (2.16±1.34 vs. 3.06±1.63, P=0.008). Conclusions Ventilatory therapy provided during a rehabilitative and interdisciplinary program increased subjects' HRQoL, executive functions and verbal memory. |
Databáze: | OpenAIRE |
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