Treatment of Congenital Microgastria
| Autor: | Larissa I. A. Ruczynski, Ivo de Blaauw, Sanne M. B. I. Botden, Horst E. Daniels-Scharbatke, Maarten Schurink |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Jejunostomy Conservative Treatment Gastroenterology Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] Enteral Nutrition Rare Diseases Internal medicine medicine Humans Statistical analysis Abnormalities Multiple Gastrostomy business.industry Microgastria medicine.disease Comorbidity Outcome parameter Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] Congenital microgastria Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10] Pediatrics Perinatology and Child Health Surgery Pouch business Digestive System Abnormalities |
| Zdroj: | European Journal of Pediatric Surgery, 31, 129-134 European Journal of Pediatric Surgery, 31, 2, pp. 129-134 |
| ISSN: | 1439-359X 0939-7248 |
| Popis: | Contains fulltext : 239093.pdf (Publisher’s version ) (Closed access) INTRODUCTION: Congenital microgastria is an extremely rare birth defect. The aim of this study was to present an overview of existing literature on the treatment of microgastria. MATERIALS AND METHODS: The term "microgastria" was used in a PubMed and Medline search. Since merely case reports were found, only a narrative synthesis with limited statistical analysis can be given. Data of different treatment modalities were collected and divided into two groups: conservative or less invasive treatment (C/LT, i.e., modified diet or a gastrostomy/jejunostomy) and extensive gastric surgery (EGS, i.e., Hunt-Lawrence pouch or total esophageal gastric dissociation). Clinical outcome parameters (nutrition, growth pattern, and mortality) were compared. RESULTS: Out of 73 articles published from 1973 to 2019, 38 articles describing 51 cases were included. In four patients, microgastria was an isolated anomaly (8%). Type of treatment was described in only 46 patients, 19 were treated by C/LT. Mortality was 9/19 (47%) in the C/LT group versus 4/27 (15%) in the EGS group (chi-square = 5.829, p = 0.016, Fisher = 0.022). There was a negative correlation between the invasiveness of the treatment and both mortality (r = -0.356, p = 0.015) and comorbidity (r = -0.506, p |
| Databáze: | OpenAIRE |
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