Electrochemical methods to enhance osseointegrated prostheses
Autor: | Mark T. Ehrensberger, Caelen M. Clark, Mary K. Canty, Eric P McDermott |
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Rok vydání: | 2019 |
Předmět: |
Titanium implant
Materials science medicine.medical_treatment 0206 medical engineering Biomedical Engineering Prosthetic limb Treatment options Review Article 02 engineering and technology Bone tissue 020601 biomedical engineering 01 natural sciences Prosthesis Osseointegration 010309 optics medicine.anatomical_structure 0103 physical sciences medicine Impedance sensing Host bone Biomedical engineering |
Zdroj: | Biomed Eng Lett |
ISSN: | 2093-985X 2093-9868 |
Popis: | Osseointegrated (OI) prosthetic limbs have been shown to provide an advantageous treatment option for amputees. In order for the OI prosthesis to be successful, the titanium implant must rapidly achieve and maintain proper integration with the bone tissue and remain free of infection. Electrochemical methods can be utilized to control and/or monitor the interfacial microenvironment where the titanium implant interacts with the biological system (host bone tissue or bacteria). This review will summarize the current understanding of how electrochemical modalities can influence bone tissue and bacteria with specific emphasis on applications where the metallic prosthesis itself can be utilized directly as a stimulating electrode for enhanced osseointegration and infection control. In addition, a summary of electrochemical impedance sensing techniques that could be used to potentially assess osseointegration and infection status of the metallic prosthesis is presented. |
Databáze: | OpenAIRE |
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