Type specific seroprevalence of bluetongue virus during 2017-2018 in Andhra Pradesh and Telangana states of India
| Autor: | Rao Pp, Bala Eshwar Raju, Kalyani Putty, B. Susmitha, Narasimha Reddy Y, M. Sharanya, Himaja K, Sairam Sandeep |
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| Rok vydání: | 2020 |
| Předmět: |
Serotype
Buffaloes 040301 veterinary sciences Cattle Diseases India Enzyme-Linked Immunosorbent Assay Biology Bluetongue Virus Serology 0403 veterinary science Vaccine strain Food Animals Age groups Seroepidemiologic Studies Prevalence Seroprevalence Animals 0402 animal and dairy science Type specific 04 agricultural and veterinary sciences 040201 dairy & animal science Virology Inactivated vaccine Animal Science and Zoology Cattle Bluetongue virus |
| Zdroj: | Tropical animal health and production. 52(6) |
| ISSN: | 1573-7438 |
| Popis: | Bluetongue (BT) is one of the important viral diseases of domestic and wild ruminants, especially small ruminants such as sheep. Out of the 29 BTV serotypes prevalent in the world, at least 24 of the serotypes are reported in India, either by virus isolation or serology. To better understand the seroprevalence of BTV, we conducted a comprehensive study in the main reservoir hosts of BTV, i.e., cattle and buffaloes of different age groups in Andhra Pradesh and Telangana states of India where the disease is majorly prevalent. A total of 321 blood samples collected from cattle and buffaloes during 2017-2018 were tested for group-specific BTV seroprevalence by c-ELISA, followed by type specific seroprevalence (against BTV-1, 2, 4, 5, 9, 12, 16, and 24) by serum neutralization test. Of the 311 BTV seropositive samples, 112, 98, 102, 127, 2, 113, 160, and 5 samples neutralized BTV-1, 2, 4, 5, 9, 12, 16, and 24, respectively. Twenty-nine samples could not neutralize any of the tested BTV serotypes. Majority of the sera neutralized more than one serotype, up to a maximum of six serotypes. Major finding of the study is detection of BTV serotypes not included in the commercial pentavalent inactivated vaccine. Regular surveillance of circulating serotypes, especially in sentinel reservoir hosts throughout the country can help in designing better multivalent vaccines with suitable vaccine strains, for specific geographic regions. |
| Databáze: | OpenAIRE |
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