Scoring Systems of Peritoneal Dissemination for the Prediction of Operative Completeness in Advanced Ovarian Cancer

Autor: SATOSHI HOSOYA, KAZU UEDA, SUGURU ODAJIMA, KOHEI OGAWA, HIROMI KOMAZAKI, TOSHIYUKI SEKI, MASATAKA TAKENAKA, MOTOAKI SAITO, HIROSHI TANABE, KYOSUKE YAMADA, HIROKUNI TAKANO, YASUSHI IIDA, NOZOMU YANAIHARA, AIKOU OKAMOTO
Rok vydání: 2021
Předmět:
Zdroj: Anticancer research. 42(1)
ISSN: 1791-7530
Popis: We investigated the predictive value of scoring systems of peritoneal disseminations for complete surgery (CS) at primary debulking surgery (PDS) in advanced ovarian cancer.We retrospectively enrolled eligible patients with clinical stages III or IVA selected for PDS from January 2015 to December 2019. Concern variables were predictive index value (PIV) and peritoneal cancer index (PCI) from operative and pathological reports. Primary endpoints were cutoffs to predict operative completeness using the receiver operating characteristic curve.Among 111 patients, PIV ≥8 and PCI ≥13 were the best predictors of incomplete PDS, including optimal and suboptimal surgeries (AUC=0.821 and 0.855, respectively). CS rates in PIV ≤6 and PCI ≤12 were significantly higher than in PIV ≥8 (89.3% vs. 47.2%; p0.05) and PCI ≥13 (90.9% vs. 41.2%: p0.05).PIV and PCI are potential predictors for CS at PDS.
Databáze: OpenAIRE