Advanced Renal-Cell Carcinoma Pseudoprogression After Combined Immunotherapy: Case Report and Literature Review
| Autor: | Lu Han, Tiepeng Li, Quanli Gao, Xiaojie Zhang, Hao Huang, Zibing Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Oncology Cancer Research medicine.medical_specialty medicine.medical_treatment cytokine-induced killer (CIK) cells Cell pseudoprogression Case Report 03 medical and health sciences 0302 clinical medicine Combined treatment Renal cell carcinoma Internal medicine Female patient PD-1 medicine renal-cell carcinoma Pseudoprogression RC254-282 Lung business.industry Cancer Neoplasms. Tumors. Oncology. Including cancer and carcinogens Immunotherapy medicine.disease 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis immunotherapy business |
| Zdroj: | Frontiers in Oncology, Vol 11 (2021) Frontiers in Oncology |
| DOI: | 10.3389/fonc.2021.640447/full |
| Popis: | Treatment with a combination of programmed cell death-1 (PD-1) blocker and cytokine-induced killer (CIK) cells has improved outcome in cancer patients but is also associated with various patterns of responses. Pseudoprogression is a unique and uncommon phenomenon with no clear criteria for rapid diagnosis. Although some reports of pseudoprogression during immunotherapy exist, there are few reports of pseudoprogression occurring twice in the same patient. Here, we report the case of 51-year-old female patient with advanced renal cell carcinoma, who received a combination treatment of PD-1 blocker and CIK cells, and where pseudoprogression of lung and brain tumors occurred successively during treatment. |
| Databáze: | OpenAIRE |
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