One-year clinical outcome of percutaneous coronary intervention with very long (≥ 40 mm) drug-eluting stent
| Autor: | Sherief Sulaiman, Haridasan Vellani, Chakanalil Govindan Sajeev, Gopalan Nair Rajesh |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty RD1-811 medicine.medical_treatment India Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Prosthesis Design 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Cause of Death Coronary stent Long coronary lesion medicine Diseases of the circulatory (Cardiovascular) system Very long DES Humans Prospective Studies cardiovascular diseases 030212 general & internal medicine Myocardial infarction PTCA Prospective cohort study Everolimus business.industry Percutaneous coronary intervention Stent Drug-Eluting Stents Middle Aged medicine.disease Coronary Vessels Interventional Cardiology Surgery Survival Rate Treatment Outcome Drug-eluting stent RC666-701 Diffuse coronary lesion Female Cardiology and Cardiovascular Medicine business Mace Follow-Up Studies medicine.drug |
| Zdroj: | Indian Heart Journal Indian Heart Journal, Vol 70, Iss, Pp S285-S289 (2018) |
| ISSN: | 0019-4832 |
| DOI: | 10.1016/j.ihj.2018.05.016 |
| Popis: | Objectives: The aim of this study was to assess the clinical outcome of patients with diffuse coronary lesions treated with very long drug-eluting coronary stents (DES) (≥ 40 mm) over a period of one year. Methods: This single-center prospective study enrolled a total of 343 consecutive patients (376 long stents) who underwent percutaneous coronary stent implantation with very long DES. One year clinical outcomes were analyzed. A subgroup analysis of diabetic patients was also performed. Results: One year follow up data was available for 314 patients (91.5%). All-cause mortality was 5 (1.6%). Eleven (3.5%) patients had non-ST-elevation myocardial infarction. Definite / probable stent thrombosis was reported in 7 (2.2%) patients. Over one year, 3 (1%) patients underwent target lesion revascularization (TLR). The total number of target lesion failure was 9 (2.9%). The rate of target lesion failure at one year was 2.6% using one vessel per patient analysis. Two patients had ischemic stroke. Any major adverse cardiac event (MACE) was observed in 19 (6%) patients. The event rates between sirolimus and everolimus stent groups were compared - cardiac death (1.7% vs 1.5%; p = 0.911), stent thrombosis (2.5% vs 1.7%; p = 0.612), TLR (1% vs 0.8%; p = 0.878), any MACE (7% vs 4.1%; p = 0.284). Exertional dyspnea was reported by 47 (15%) patients at the end of one year. Dual antiplatelet adherence rate was 96% (n = 301 of 314). Conclusion: Use of very long stents (≥40 mm) for diffuse coronary lesions is safe and effective with acceptably low event rates. No significant differences in event rates were observed between the types of DES used in this study (Sirolimus Vs. everolimus). Keywords: Very long DES, Diffuse coronary lesion, PTCA, Long coronary lesion |
| Databáze: | OpenAIRE |
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