New Off–On Sensor for Captopril Sensing Based on Photoluminescent MoOx Quantum Dots
| Autor: | Xiao Jing Zhao, Guo Qing Liu, Sai Jin Xiao, Zhao Jun Chu, Li Zhang, Han Xu, Cheng Zhi Huang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Detection limit
Photoluminescence Materials science 010405 organic chemistry General Chemical Engineering Molybdenum oxide Nanotechnology 02 engineering and technology General Chemistry 021001 nanoscience & nanotechnology 01 natural sciences Thiol group Article 0104 chemical sciences Catalysis Nanomaterials lcsh:Chemistry Linear relationship lcsh:QD1-999 Quantum dot 0210 nano-technology |
| Zdroj: | ACS Omega ACS Omega, Vol 2, Iss 4, Pp 1666-1671 (2017) |
| ISSN: | 2470-1343 |
| Popis: | Molybdenum oxide nanomaterials have recently attracted widespread attention for their unique optical properties and catalytic performance. However, until now, there is little literature on the application of photoluminescent molybdenum oxide nanomaterials in biological and pharmaceutical sensing. Herein, photoluminescent molybdenum oxide quantum dots (MoOx QDs) were synthesized via a facile method, and then, the synthesized MoOx QDs were further applied as a new type of photoluminescent probe to design a new off–on sensor for captopril (Cap) determination on the basis of the fact that the quenched photoluminescence of MoOx QDs by Cu2+ was restored with Cap through specific interaction between the thiol group of Cap and Cu2+. Under optimal conditions, the restored photoluminescence intensity showed a good linear relationship with the content of Cap, ranging from 1.0 to 150.0 μM, with a limit of detection of 0.51 μM (3σ/k). Additionally, the content of Cap in pharmaceutical samples was successfully detected with the newly developed off–on sensor, and the recoveries were 99.4–101.7%, which suggest that the present off–on sensor has a high accuracy. |
| Databáze: | OpenAIRE |
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