Repeat Femoral Arteriography in Hyperlipidemic Patients
| Autor: | G. Ruhn, A. Hemmingsson, A. G. Olsson, Gunnar Helmius, Uno Erikson |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Atheromatous disease
medicine.medical_specialty Fenofibrate Radiological and Ultrasound Technology business.industry Femoral arteriography General Medicine Femoral artery 030204 cardiovascular system & hematology medicine.disease Asymptomatic Intermittent claudication 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine.artery Hyperlipidemia medicine Radiology Nuclear Medicine and imaging Radiology Lipid lowering medicine.symptom business medicine.drug |
| Zdroj: | Acta Radiologica. 29:303-309 |
| ISSN: | 1600-0455 0284-1851 |
| DOI: | 10.1177/028418518802900309 |
| Popis: | Femoral arteriography was performed in 62 patients with significant hyperlipidemia. Sixty were asymptomatic and two had intermittent claudication. The patients participated in a study aiming to demonstrate whether serum lipid lowering by drugs could influence the development of femoral artery atheromatous disease. Half of the patients were treated with fenofibrate and nicotinic acid and the other half served as a control group. At the first arteriography atherosclerotic lesions were found in 46 of the 62 patients (74%). Arteriography was repeated up to three times without complications. Visual analysis of angiograms revealed considerable inter-observer variation. An attempt was made to assess the angiograms by a computerized method which, however, still needs improvement and a computer designed for image analysis. Most patients had small or moderate atheromatous deposits in the femoral artery at the initial examination, in most cases showing no change during the study period of 18 months. Regression was found in five patients of the treated group, but in none of the control patients as judged by visual gradation (p |
| Databáze: | OpenAIRE |
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