Offering self-sampling to cervical screening non-attenders in primary care
| Autor: | A. Hollingworth, Anita W. W. Lim, Sebastian Kalwij, Peter Sasieni, Geoffrey M. Curran |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Uterine Cervical Neoplasms Primary care Cervical intraepithelial neoplasia State Medicine Specimen Handling 03 medical and health sciences Young Adult 0302 clinical medicine London Medicine Humans Mass Screening 030212 general & internal medicine Young adult Human papillomavirus Mass screening Cervical screening Primary Health Care business.industry Obstetrics Health Policy Papillomavirus Infections Public Health Environmental and Occupational Health Middle Aged medicine.disease Uterine Cervical Dysplasia Multicenter study 030220 oncology & carcinogenesis Physical therapy Patient Compliance Female business Self sampling |
| Zdroj: | Journal of medical screening. 24(1) |
| ISSN: | 1475-5793 |
| Popis: | Objectives To assess the feasibility and acceptability of offering self-sampling for Human Papillomavirus (HPV) testing to cervical screening non-attenders when they consult primary care for any reason. Methods In a pilot implementation study, six general practices in London, UK, offered self-sampling kits during consultation to women aged 25–64 who were at least six months overdue for cervical screening (no cytology test recorded in the past 3.5 years if aged 25–49, or 5.5 years if aged 50–64). Eligible women were identified using an automated real-time search (during consultation) of the general practice electronic medical record system. Women collected samples either in clinic or at home (dry flocked swabs analysed using Roche Cobas®4800). Results Of approximately 5000 eligible women, 3131 consulted primary care between January and December 2014 (mean recruitment period 9.5 months). Of these, 21% (652) were offered kits, 14% (443) accepted, and 9% (292) returned a self-sample. The proportion of eligible women offered kits varied considerably among practices (11–36%). Sample return rates increased with kit offered rates ( r = 0.8, p = 0.04). Of 39 HPV positive women 85% (33) attended follow-up, including two with invasive cancers (stage 2A1 and 1A1). Conclusions Offering self-sampling to cervical screening non-attenders opportunistically in primary care is feasible. Return rates could be increased if more women were offered kits. A large trial is needed to identify how self-sampling is best integrated into the national screening programme, and to identify determinants of uptake. |
| Databáze: | OpenAIRE |
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