Immunoexpression of tryptase-positive mast cells in periapical granulomas and radicular cysts
| Autor: | H. Costa Neto, R. de Almeida Freitas, Manuel Antonio Gordón-Núñez, Hébel Cavalcanti Galvão, A. L. D. L. de Andrade |
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| Rok vydání: | 2014 |
| Předmět: |
Inflammation
Radicular Cyst Pathology medicine.medical_specialty biology business.industry Periapical Granuloma Tryptase Epithelium Immunoenzyme Techniques Lesion biology.protein Humans Immunohistochemistry Medicine Tryptases Periapical Diseases Mast Cells Antibody medicine.symptom business General Dentistry Immunostaining |
| Zdroj: | International Endodontic Journal. 48:729-735 |
| ISSN: | 0143-2885 |
| DOI: | 10.1111/iej.12366 |
| Popis: | Aim To evaluate and compare the immunoexpression of tryptase in samples of periapical granulomas (PGs) and radicular cysts (RCs) correlating it with the type of lesion, localization, intensity of the inflammatory infiltrate and thickness of the cystic epithelial lining, in order to gain insight into the phlogistic role of these cells in the lesions studied. Methodology Twenty-five PGs and twenty-five RCs obtained from human teeth without endodontic treatment were submitted to morphological and immunohistochemical analysis using anti-tryptase antibody. Mast cells were identified and counted in three regions: intra-epithelial, central/superficial and deep portions. The data were analysed using the Mann–Whitney U-test (P |
| Databáze: | OpenAIRE |
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