Functional and oncological outcomes of salvage external beam radiotherapy following robot-assisted radical prostatectomy in a Canadian cohort
| Autor: | Cristina Negrean, Pierre-Alain Hueber, Roger Valdivieso, Pierre I. Karakiewicz, Emad Rajih, Mansour Alnazari, Assaad El-Hakim, Guila Delouya, Marc Zanaty, Khaled Ajib, Daniel Taussky, Mila Mansour, Kevin C. Zorn |
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| Rok vydání: | 2017 |
| Předmět: |
Biochemical recurrence
medicine.medical_specialty Urinary continence business.industry Prostatectomy Urology medicine.medical_treatment medicine.disease Prostate cancer medicine.anatomical_structure Oncology Prostate Cohort Medicine International Prostate Symptom Score External beam radiotherapy business human activities Original Research |
| Zdroj: | Canadian Urological Association Journal. 12:45-9 |
| ISSN: | 1920-1214 1911-6470 |
| DOI: | 10.5489/cuaj.4641 |
| Popis: | Introduction: We sought to determine the impact of salvage radiotherapy (SRT) on oncological and functional outcomes of patients with prostate cancer after biochemical recurrence (BCR) following robot-assisted radical prostatectomy (RARP).Methods: Data of 70 patients with prostate cancer treated with SRT after developing BCR were retrospectively analyzed from a prospectively collected RARP database of 740 men. Oncological (prostate- specific antigen [PSA]) and functional (pads/day, International Prostate Symptom Score [IPSS], and Sexual Health Inventory for Men [SHIM]) outcomes were reported at six, 12, and 24 months after RT and adjusted for pre-SRT status.Results: Men who underwent SRT had a mean age, PSA, and time from radical prostatectomy (RP) to RT of 61.8 years (60.1‒63.6), 0.5 ng/ml (0.2‒0.8), and 458 days (307‒747), respectively. Freedom from biochemical failure (FFBF) post-SRT, defined as a PSA nadir |
| Databáze: | OpenAIRE |
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