17 Alpha-Hydroxylase/17,20-Lyase Deficiency: A Rare Cause of Endocrine Hypertension
| Autor: | Dominique Maiter, Cedric Hermans, Philippe De Nayer, Jean-François de Plaen |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
medicine.medical_specialty
business.industry General Medicine Hyperplasia medicine.disease Hyperaldosteronism Endocrine hypertension Lyase deficiency Endocrinology CYP17A1 Internal medicine Male pseudohermaphroditism Etiology medicine Congenital adrenal hyperplasia Amenorrhea medicine.symptom business |
| Zdroj: | The American Journal of the Medical Sciences. 312:126-129 |
| ISSN: | 0002-9629 |
| Popis: | The combination of hypertension, hypokaliemia, and male pseudohermaphroditism or amenorrhea must prompt a search for a rare adrenal enzymatic defect, α -hydroxylase/17,20-lyase deficiency. This is a report of the observation of a male patient in whom this rare deficit was diagnosed in adulthood on the basis of lifelong ambiguous external genitalia, hypogonadism, severe hypertension, bilateral adrenal hyperplasia, and biological markers evoking an excess of mineralocorticoids without hyperal-dosteronism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|