Polysaccharide fraction from the Indian mistletoe, Dendrophthoe falcata (L.f.) Ettingsh enhances innate immunity and disease resistance in Oreochromis niloticus (Linn.)
| Autor: | Konda Subramanian Shalini, Omita Yengkhom, R. Dinakaran Michael, Parasuraman Aiya Subramani |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Aquaculture Aquatic Science Biology Plant disease resistance Polysaccharide Immune related genes 03 medical and health sciences Fish Diseases Polysaccharides Environmental Chemistry Animals Disease Resistance chemistry.chemical_classification Innate immune system Traditional medicine Plant Extracts Dendrophthoe falcata 04 agricultural and veterinary sciences General Medicine Cichlids biology.organism_classification Animal Feed Immunity Innate Aeromonas hydrophila Mistletoe Plant Leaves Oreochromis 030104 developmental biology chemistry Dietary Supplements 040102 fisheries 0401 agriculture forestry and fisheries Fish Gram-Negative Bacterial Infections Feeding Regimen |
| Zdroj: | Fishshellfish immunology. 88 |
| ISSN: | 1095-9947 |
| Popis: | The polysaccharide fraction (PF) isolated from the hemiparasitic mistletoe, Dendrophthoe falcata (L.f.) Ettingsh (DF) leaves was tested for its immunostimulatory properties in Oreochromis niloticus (Linn.). Different groups of experimental fish were fed for 1, 2 or 3 weeks with three different doses [low (0.01%), mid (0.1%), or high (1%)] of D. falcata polysaccharide fraction (DFPF) - supplemented diet. After every feeding regimen, the fish were assessed for non-specific immunological parameters, immune related gene expression and disease protection. The DFPF treated groups showed significant (P 0.05) enhancement of non-specific immune parameters. Significant (P 0.05) upregulation of lysozyme and TNF-α gene expression was observed in DFPF treated groups. In pathogen challenge studies using Aeromonas hydrophila, the DFPF treated groups displayed significant (P 0.05) decrease in percentage mortality and the consequent increase in relative percent survival (RPS). Supplementation of 1% DFPF in the feed for a week conferred the maximum protection against the virulent pathogen challenge, recording a RPS of 100. These results suggest that DFPF has the potential to be used as an immunostimulating feed additive in finfish aquaculture. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect