Effect of different low-level intensity laser therapy (LLLT) irradiation protocols on the osseointegration of implants placed in grafted areas
| Autor: | Elcio Marcantonio, Rosemary Adriana Chierici Marcantonio, Mauricio Andrés Tinajero Aroni, Felipe Eduardo Pinotti, Guilherme José Pimentel Lopes de Oliveira |
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| Přispěvatelé: | Universidade Federal de Uberlândia (UFU), Universidade Estadual Paulista (Unesp), Universidade Federal de Sergipe (UFS) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Ceramics
Materials science Removal torque Bone healing Bone morphogenetic protein 2 Osseointegration 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Laser therapy Animals Irradiation Tibia Low-Level Light Therapy General Dentistry Dental Implants Bone substitutes RK1-715 030206 dentistry Graft procedure Rats Dentistry Cattle Original Article Low-level intensity laser therapy Biomedical engineering |
| Zdroj: | Journal of Applied Oral Science v.29 2021 Journal of applied oral science Universidade de São Paulo (USP) instacron:USP Journal of Applied Oral Science, Volume: 29, Article number: e20200647, Published: 14 APR 2021 Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Journal of Applied Oral Science Journal of Applied Oral Science, Vol 29 (2021) |
| ISSN: | 1678-7757 |
| Popis: | Made available in DSpace on 2021-06-25T10:59:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01. Added 1 bitstream(s) on 2021-07-15T15:24:02Z : No. of bitstreams: 1 S1678-77572021000100416.pdf: 7330362 bytes, checksum: 176f9397e90a7aaa56dbc8307d46ba4a (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Objective: To evaluate the effect of different protocols of low-level intensity laser therapy (LLLT) irradiation on the osseointegration of implants placed in grafted areas. Methodology: 84 rats were randomly allocated into six groups: DBB: defect filled with deproteinized bovine bone; HA/TCP: defect filled with biphasic ceramic of hydroxyapatite/β-tricalcium phosphate; DBB-LI: defect filled with DBB and treated with LLLT after implant placement; HA/TCP-LI: defect filled with HA/TCP and treated with LLLT after implant placement; DBB-LIB: defect filled with DBB and treated with LLLT after graft procedure and implant placement; and HA/TCP-LIB: defect filled HA/TCP and treated with LLLT after graft procedure and implant placement. The bone defects were made in the tibia and they were grafted. After 60 days, the implants were placed. The rats were subsequently subjected to euthanasia 15 and 45 days after implant placement. The pattern of osseointegration and bone repair in the grafted area was evaluated by biomechanical, microtomographic, and histometric analyses. Furthermore, the expression of bone biomarker proteins was assessed. Results: The LLLT groups presented higher removal torque, mineralized tissue volume, and a greater degree of osseointegration, especially when LLLT was performed only after implant placement, and these findings were associated with higher expression of BMP2 and alkaline phosphatase. Conclusion: LLLT performed on implants placed in grafted areas enhances the osseointegration process. Universidade Federal de Uberlândia (FOUFU) Faculdade de Odontologia da Uberlândia Departamento de Periodontia/Implantodontia Universidade Estadual Paulista (UNESP) Faculdade de Odontologia de Araraquara Departmento de Diagnóstico e Cirurgia Universidad San Francisco de Quito (UFSQ) Departamento de Periodoncia Universidade Estadual Paulista (UNESP) Faculdade de Odontologia de Araraquara Departmento de Diagnóstico e Cirurgia FAPESP: 2013/24318-0 CNPq: 459984/2014-4. |
| Databáze: | OpenAIRE |
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