Intraoperative use of a functional lumen imaging probe during peroral endoscopic myotomy in patients with achalasia: A single-institute experience and systematic review
Autor: | Hyeon Jeong Goong, Shin Hee Kim, Su Jin Hong |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Myotomy
medicine.medical_treatment General Anesthesia Achalasia Laryngology Intraoperative Period 0302 clinical medicine Anesthesiology Medicine and Health Sciences Medicine Anesthesia Multidisciplinary medicine.diagnostic_test Pharmaceutics Dysphagia Research Assessment Chemistry Treatment Outcome Barium 030220 oncology & carcinogenesis Physical Sciences 030211 gastroenterology & hepatology Radiology Esophagoscopy medicine.symptom Anatomy Research Article Chemical Elements medicine.medical_specialty Systematic Reviews Imaging Techniques Science Lumen (anatomy) Surgical and Invasive Medical Procedures Research and Analysis Methods 03 medical and health sciences Esophagus Drug Therapy Diagnostic Medicine Humans Reflux esophagitis business.industry Biology and Life Sciences Endoscopy medicine.disease Gastrointestinal Tract Esophageal Achalasia Otorhinolaryngology business Esophagitis Digestive System |
Zdroj: | PLoS ONE, Vol 15, Iss 6, p e0234295 (2020) PLoS ONE |
ISSN: | 1932-6203 |
Popis: | AimThe functional lumen imaging probe (FLIP) is a recently developed technique to evaluate the esophagogastric junction (EGJ) distensibility. Unlike timed barium esophagogram (TBE) and high-resolution manometry (HRM), FLIP can be used during peroral endoscopic myotomy (POEM). The aim of this study was to evaluate the association of intraoperative FLIP parameters with clinical outcomes as recorded in a single-center database and to investigate a systematic review of literatures.MethodsWe reviewed consecutive patients diagnosed with achalasia and scheduled for POEM between June 2016 and March 2019 in our tertiary referral hospital. All patients underwent intraoperative FLIP assessment during POEM. The final FLIP measurements were compared between the patients with good and poor clinical response. We comprehensively reviewed studies evaluating whether intraoperative FLIP measurements reflected clinical outcomes.ResultsWe evaluated 23 patients with achalasia who underwent intraoperative FLIP before and after POEM. Two exhibited poor clinical responses after 3 months (Eckardt scores = 3). The final distensibility index (DI) did not differ significantly between good and poor responders (5.01 [4.52] vs. 4.91 [3.63-6.20] mm2/mmHg at a balloon distension of 50-mL, median [IQR], P = 0.853). The final DI did not differ significantly between post-POEM reflux esophagitis and non-reflux esophagitis groups (6.20 [5.15] vs. 4.23 [1.79] mm2/mmHg at a balloon distension of 50-mL, median [IQR], P = 0.075).ConclusionsA systematic review of both prospective and retrospective studies including our data indicated that the final intraoperative FLIP measurements did not differ significantly between good and poor responders. Further study with more patients is necessary to explore whether FLIP can predict short- and long-term clinical responses. |
Databáze: | OpenAIRE |
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