Echocardiographic evolution of pulmonary artery pressure after acute pulmonary embolism. Results from IPER registry
| Autor: | Girolamo Arrigo, Amedeo Bongarzoni, Chiara Forgione, Claudio Cuccia, Irene Floriani, Franco Casazza, Luigi Pignataro, Ferdinando Imperadore |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.medical_treatment Hypertension Pulmonary Blood Pressure Comorbidity Pulmonary Artery Young Adult Recurrence Risk Factors medicine.artery Internal medicine medicine Humans Registries Aged Aged 80 and over business.industry Incidence Mean age Blood Pressure Determination Hematology Thrombolysis Middle Aged medicine.disease Prognosis Pulmonary hypertension Echocardiography Doppler Pulmonary embolism Causality Blood pressure Italy Pulmonary artery Hospital admission Acute Disease Cardiology Disease Progression Population study Female business Pulmonary Embolism |
| Zdroj: | Thrombosis research. 134(6) |
| ISSN: | 1879-2472 |
| Popis: | Aims The aim of the study is to describe the course of the echocardiographically measured pulmonary artery systolic pressure (PAsP) in a series of patients included in the Italian Pulmonary Embolism Registry (IPER). Methods Patients with confirmed PE received an echo-Doppler evaluation within 24 hours from hospital admission and after one year. Pulmonary hypertension (PH) was considered “likely” , “possible” or “unlikely” with a right ventricular-right atrial (RV-RA) pressure gradient > 45 mm Hg, between 32 and 45 mm Hg and ≤ 31 mm Hg and no additional echocardiographic variables suggestive of PH, respectively. Results We studied 286 patients (169 females and 117 males, mean age 67 ± 15; mean follow-up 387 ± 45 days): 240 had a baseline tricuspid regurgitation (TR) and a RV-RA gradient of variable degree. PH was considered likely, unlikely and possible in 97, 93 and 50 patients respectively. At FU echocardiography, 6 patients (2.1%) had a likely PH and all of them were part of the group of 97 patients with a baseline likely PH; 24 patients (8.4%) had a possible PH, and 67% of them had an initial likely PH. No patients with a baseline unlikely PH or without TR developed a follow-up PH (both likely or possible). The probability to show a likely PH at FU echocardiography for patients with a baseline RV-RA gradient > 45 mm Hg was 6.2%, while the probability not to have a likely PH for patients with a baseline RV-RA gradient ≤ 45 mm Hg was 100%. Conclusion In our study population of patients with acute PE, we observed that those presenting with a baseline echocardiographic RV-RA pressure gradient ≤ 45 mm Hg were completely free from a likely PH after 1-year. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect