Outcomes and organ dysfunctions of critically ill patients with systemic lupus erythematosus and other systemic rheumatic diseases
Autor: | C.E. Moraes, Samuel Katsuyuki Shinjo, Lcp Azevedo, Marcelo Park, F.P. Giannini, Juliana V. Pinaffi, Otavio T. Ranzani, Ligia C. Battaini, Luis Felipe Lopes Prada |
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Rok vydání: | 2011 |
Předmět: |
Adult
Male medicine.medical_specialty Physiology Critical Illness Multiple Organ Failure Immunology Biophysics Biochemistry immune system diseases Rheumatic Diseases Internal medicine medicine Humans Lupus Erythematosus Systemic Respiratory function General Pharmacology Toxicology and Pharmaceutics Respiratory system skin and connective tissue diseases Intensive care medicine Critically ill business.industry General Neuroscience Incidence (epidemiology) Respiratory dysfunction Cell Biology General Medicine Length of Stay Middle Aged Respiration Disorders Hematologic Diseases Icu admission Hospitalization Intensive Care Units Respiratory failure Shock (circulatory) Kidney Failure Chronic Female medicine.symptom Epidemiologic Methods business |
Zdroj: | Brazilian Journal of Medical and Biological Research. 44:1184-1193 |
ISSN: | 0100-879X |
Popis: | Our objective was to compare the pattern of organ dysfunctions and outcomes of critically ill patients with systemic lupus erythematosus (SLE) with patients with other systemic rheumatic diseases (SRD). We studied 116 critically ill SRD patients, 59 SLE and 57 other-SRD patients. The SLE group was younger and included more women. Respiratory failure (61%) and shock (39%) were the most common causes of ICU admission for other-SRD and SLE groups, respectively. ICU length-of-stay was similar for the two groups. The 60-day survival adjusted for the groups’ baseline imbalances was not different (P = 0.792). Total SOFA scores were equal for the two groups at admission and during ICU stay, although respiratory function was worse in the other-SRD group at admission and renal and hematological functions were worse in the SLE group at admission. The incidence of severe respiratory dysfunction (respiratory SOFA >2) at admission was higher in the other-SRD group, whereas severe hematological dysfunction (hematological SOFA >2) during ICU stay was higher in the SLE group. SLE patients were younger and displayed a decreased incidence of respiratory failure compared to patients with other-SRDs. However, the incidences of renal and hematological failure and the presence of shock at admission were higher in the SLE group. The 60-day survival rates were similar. |
Databáze: | OpenAIRE |
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