Uric acid as a factor in the metabolic syndrome
| Autor: | Rodolfo Leão Borges, Artur Beltrame Ribeiro, Marcelo Costa Batista, Maria Teresa Zanella |
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| Rok vydání: | 2010 |
| Předmět: |
Nephrology
Male medicine.medical_specialty Physiology Hyperuricemia urologic and male genital diseases Global Health Kidney chemistry.chemical_compound Insulin resistance Sex Factors Risk Factors Internal medicine Internal Medicine medicine Prevalence Humans Clinical significance Metabolic Syndrome business.industry nutritional and metabolic diseases medicine.disease Prognosis Uric Acid Serum urate Endocrinology medicine.anatomical_structure chemistry Cardiovascular Diseases Uric acid Female Kidney Diseases Metabolic syndrome Insulin Resistance business Biomarkers Brazil |
| Zdroj: | Current hypertension reports. 12(2) |
| ISSN: | 1534-3111 |
| Popis: | Hyperuricemia is a prevalent finding in patients presenting metabolic syndrome, although its clinical meaning is still controversial and often underestimated. Men and women have different serum urate levels at all ages, and the impact of hyperuricemia in cardiovascular and renal outcomes is generally associated with a worse prognosis in women. Recent studies also have called attention to another perspective on hyperuricemia, indicating that it may be not only a consequence of insulin resistance states but also a significant predictor of the development of metabolic syndrome. This review discusses recent evidence related to the clinical significance of hyperuricemia in both sexes and the potential benefits of lowering serum uric acid levels. |
| Databáze: | OpenAIRE |
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