Analysis of intracellular enzymes in saliva of patients with aggressive periodontitis
| Autor: | Biljana Andjelski-Radicevic, Biljana Milicic, Zana Popovic, Zlata Brkic, Ivan Dozic |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Saliva ALT Ocean Engineering digestive system Gastroenterology 03 medical and health sciences 0302 clinical medicine stomatognathic system Internal medicine medicine Aggressive periodontitis Young adult AST chemistry.chemical_classification saliva 030222 orthopedics biology business.industry Healthy subjects 030206 dentistry medicine.disease intracellular enzymes aggressive periodontitis Enzyme assay 3. Good health lcsh:RK1-715 Enzyme chemistry lcsh:Dentistry Immunology biology.protein ALP Alkaline phosphatase business Intracellular |
| Zdroj: | Stomatološki glasnik Srbije, Vol 60, Iss 3, Pp 155-160 (2013) |
| ISSN: | 1452-3701 0039-1743 |
| Popis: | Introduction. Aggressive periodontitis is characterized by rapid destruction of periodontal tissue. It is more commonly found in young adults. Analysis of biochemical markers in saliva is very important to monitor the level of periodontal tissue destruction. The aim of this study was to analyze the intracellular enzymes aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the saliva of patients with aggressive periodontitis. Material and Methods. The study included 22 patients with aggressive periodontitis and 28 healthy subjects (control group). Enzyme activity was measured in mixed non-stimulated saliva using kinetic methods in a spectrophotometer and expressed in international units per litre (U/L). Results. The activity of enzymes ALT and ALP was significantly higher in saliva of patients with aggressive periodontitis compared to healthy subjects, while AST activity was not significantly different. Also, there was no correlation between the activity of intracellular enzymes in saliva and clinical parameters such as gingival index, bleeding index, probing depth in patients with aggressive periodontitis. Conclusion. Obtained results indicate that salivary enzymes AST, ALT and ALP can be used as biochemical markers to aid in diagnosis of aggressive periodontitis. |
| Databáze: | OpenAIRE |
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