STUDIES ON THE ACTIVATION OF SERUM PROTEASE BY AN ANTIGEN-ANTIBODY SYSTEM

Autor:	John A. Flick, Joseph V. Jemski, Warren R. Stinebring
Rok vydání:	1953
Předmět:	Protease Ovalbumin medicine.medical_treatment Guinea Pigs Immunology Albumin Biology Precipitin Molecular biology Article In vitro Guinea pig Biochemistry Antigen Albumins medicine biology.protein Animals Humans Immunology and Allergy Fibrinolysin Rabbits Antibody
Zdroj:	The Journal of Experimental Medicine
ISSN:	1540-9538 0022-1007
Popis:	The results obtained in this study indicate that serum protease is not activated by either a rabbit or guinea pig antiovalbumin-ovalbumin system, in vitro. A precipitin reaction occurring in the presence of a serum protease precursor of three species (human, rabbit, and guinea pig) failed to activate the protease precursor. Furthermore, particulate material as preformed precipitates could not be shown to activate the protease of either human or rabbit serum or their euglobulin fractions. The material presented seems to be further evidence against the postulated role of serum protease in immunologic systems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331d08e6860c964a559d1b25af10d44a https://doi.org/10.1084/jem.97.3.439 Zobrazit plný text záznamu