Relation of the metabolic syndrome with proarrhythmogenic electrocardiographic parameters in patients without overt diabetes
| Autor: | Turgay, Isik, Ibrahim H, Tanboga, Mustafa, Kurt, Ahmet, Kaya, Mehmet, Ekinci, Erkan, Ayhan, Mahmut, Uluganyan, Mehmet, Ergelen, Tolga S, Guvenc, Servet, Altay, Huseyin, Uyarel |
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| Přispěvatelé: | ULUGANYAN, MAHMUT |
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Metabolic Syndrome Arrhythmias Cardiac General Medicine Middle Aged Risk Assessment Sensitivity and Specificity Severity of Illness Index Body Mass Index Electrocardiography Heart Conduction System Heart Rate Predictive Value of Tests Case-Control Studies Diabetes Mellitus Exercise Test Humans Female Cardiology and Cardiovascular Medicine Algorithms Ultrasonography |
| Zdroj: | Acta Cardiologica. 67:195-201 |
| ISSN: | 0373-7934 0001-5385 |
| DOI: | 10.1080/ac.67.2.2154210 |
| Popis: | Objectives We aimed to observe the relationship of the metabolic syndrome and proarrythmogenic ECG parameters and to evaluate a possible correlation of these parameters to the metabolic syndrome score in patients without overt diabetes mellitus. Methods The study population consisted of 142 patients with the metabolic syndrome and 170 age- and gender-matched control subjects. In the ECG recordings, resting heart rate, QRS duration, corrected QT duration and corrected QT dispersion were measured. Patients were classifi ed into three groups based on number of fulfi lled metabolic syndrome criteria: group 1 (three metabolic syndrome criteria), group 2 (four metabolic syndrome criteria) and group 3 (fi ve metabolic syndrome criteria). Results Patients with the metabolic syndrome had a higher increased resting heart rate, QTcd, prolonged QRS and QTc duration. Resting heart rate increases signifi cantly parallel to the increase in the metabolic syndrome score across the groups, whilst QRS duration remained unchanged. QTc duration and QTc dispersion were signifi cantly higher in groups 2 and 3 when compared to group 1. However, no signifi cant diff erences were observed between groups 2 and 3. Conclusion We demonstrated that the metabolic syndrome and its score related with increased resting heart rate and prolonged repolarization durations in patiens without overt diabetes mellitus. These pro arrhythmogenic parameters could be used in the development of risk stratifi cation schemes for sudden cardiac death in patients with the metabolic syndrome. |
| Databáze: | OpenAIRE |
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