Better skeletal microstructure confers greater mechanical advantages in Chinese-American women versus white women
| Autor: | Julia Udesky, Donald J. McMahon, George Liu, John P. Bilezikian, X. Sherry Liu, X. Edward Guo, Marcella D. Walker |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Endocrinology Diabetes and Metabolism Article White People Bone volume fraction Trabecula medicine Humans Orthopedics and Sports Medicine Tibia Quantitative computed tomography Life Style Chinese americans Bone mineral Asian medicine.diagnostic_test business.industry Organ Size Anatomy Distal tibia Biomechanical Phenomena Radius Trabecular bone medicine.anatomical_structure Female Tomography X-Ray Computed Nuclear medicine business |
| Zdroj: | Journal of Bone and Mineral Research. 26:1783-1792 |
| ISSN: | 0884-0431 |
| DOI: | 10.1002/jbmr.378 |
| Popis: | Despite lower areal bone mineral density (aBMD), Chinese-American women have fewer fractures than white women. We hypothesized that better skeletal microstructure in Chinese-American women in part could account for this paradox. Individual trabecula segmentation (ITS), a novel image-analysis technique, and micro–finite-element analysis (µFEA) were applied to high-resolution peripheral quantitative computed tomography (HR-pQCT) images to determine bone microarchitecture and strength in premenopausal Chinese-American and white women. Chinese-American women had 95% and 80% higher plate bone volume fraction at the distal radius and tibia, respectively, as well as 20% and 18% higher plate number density compared with white women (p |
| Databáze: | OpenAIRE |
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