Patients' perception of stopping or continuing treatment of cervical dystonia with botulinum toxin type A
| Autor: | Allison Brashear, Joanne Wojcieszek, Kathleen Bergan, Walter T. Ambrosius, Eric Siemers |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Patient Dropouts Dose Neurological disorder complex mixtures Injections Intramuscular medicine Adverse Drug Reaction Reporting Systems Humans Botulism Cervical dystonia Botulinum Toxins Type A Adverse effect Torticollis Aged Dystonia business.industry Middle Aged medicine.disease Botulinum toxin Treatment Outcome Neurology Patient Satisfaction Anesthesia Female Neurology (clinical) business medicine.drug |
| Zdroj: | Movement disorders : official journal of the Movement Disorder Society. 15(1) |
| ISSN: | 0885-3185 |
| Popis: | Despite widespread commercial acceptance of botulinum toxin (BTX) for idiopathic cervical dystonia (ICD), no follow up has been performed to determine when and why some patients stop therapy. It has been suggested that some patients who stop BTX treatment may do so because of permanent improvement.1 We surveyed 155 patients with ICD who were treated over 6 years with BTX to determine when and why patients stopped treatment with BTX, and what adverse events and changes in dose and/or frequency of treatments occurred in those who continued treatment. Of the 133 (86.6%) individuals returning the surveys, 104 continued on BTX treatment and 29 had stopped therapy. Of the 29 subjects no longer receiving BTX, 11 individuals had only received one or two injections. Prior surgical treatment for ICD did not influence their decision to stop therapy. Of those 104 of 133 continuing on BTX treatments, two thirds of the subjects reported the injections always help, whereas one quarter estimated one set of injections did not help. One third of those continuing treatment reported the first injection was most helpful, whereas another one third felt all injections were similarly effective. After an initial adjustment, BTX dosages and frequency of treatment remained stable in this group. |
| Databáze: | OpenAIRE |
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