L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms : Nausea, Headache, Stress and Anxiety
Autor: | Olli Kärkkäinen, Joonas E Salminen, Tommi Möykkynen, C.J. Peter Eriksson, Jussi Kauhanen, Heikki Mäkisalo, Markus Metsälä, Maria Palmén |
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Přispěvatelé: | Clinicum, Department of Public Health, Department of Chemistry, University of Helsinki, Receptor Biochemistry, Molecular and Integrative Biosciences Research Programme, Biosciences, HUS Abdominal Center, IV kirurgian klinikka, Oral and Maxillofacial Surgery |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male TOBACCO-SMOKE medicine.medical_specialty Nausea Alcohol Anxiety Placebo Tobacco smoke law.invention 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Randomized controlled trial Double-Blind Method law Internal medicine ETHANOL Medicine Humans 030212 general & internal medicine Cysteine Young adult ACETALDEHYDE SCALE business.industry Acetaldehyde Headache 3112 Neurosciences EXTRACT General Medicine Vitamins Middle Aged 3142 Public health care science environmental and occupational health 3. Good health chemistry Dietary Supplements medicine.symptom business Alcoholic Intoxication 030217 neurology & neurosurgery |
Popis: | AimsAlcohol-related hangover symptoms: nausea, headache, stress and anxiety cause globally considerable amount of health problems and economic losses. Many of these harmful effects are produced by alcohol and its metabolite, acetaldehyde, which also is a common ingredient in alcohol beverages. The aim of the present study is to investigate the effect of the amino acid L-cysteine on the alcohol/acetaldehyde related aftereffects.MethodsVoluntary healthy participants were recruited through advertisements. Volunteers had to have experience of hangover and/or headache. The hangover study was randomized, double-blind and placebo-controlled. Nineteen males randomly swallowed placebo and L-cysteine tablets. The alcohol dose was 1.5 g/kg, which was consumed during 3 h.ResultsThe primary results based on correlational analysis showed that L-cysteine prevents or alleviates hangover, nausea, headache, stress and anxiety. For hangover, nausea and headache the results were apparent with the L-cysteine dose of 1200 mg and for stress and anxiety already with the dose of 600 mg.ConclusionsL-cysteine would reduce the need of drinking the next day with no or less hangover symptoms: nausea, headache, stress and anxiety. Altogether, these effects of L-cysteine are unique and seem to have a future in preventing or alleviating these harmful symptoms as well as reducing the risk of alcohol addiction. |
Databáze: | OpenAIRE |
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