L-Cysteine Containing Vitamin Supplement Which Prevents or Alleviates Alcohol-related Hangover Symptoms : Nausea, Headache, Stress and Anxiety

Autor: Olli Kärkkäinen, Joonas E Salminen, Tommi Möykkynen, C.J. Peter Eriksson, Jussi Kauhanen, Heikki Mäkisalo, Markus Metsälä, Maria Palmén
Přispěvatelé: Clinicum, Department of Public Health, Department of Chemistry, University of Helsinki, Receptor Biochemistry, Molecular and Integrative Biosciences Research Programme, Biosciences, HUS Abdominal Center, IV kirurgian klinikka, Oral and Maxillofacial Surgery
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Popis: AimsAlcohol-related hangover symptoms: nausea, headache, stress and anxiety cause globally considerable amount of health problems and economic losses. Many of these harmful effects are produced by alcohol and its metabolite, acetaldehyde, which also is a common ingredient in alcohol beverages. The aim of the present study is to investigate the effect of the amino acid L-cysteine on the alcohol/acetaldehyde related aftereffects.MethodsVoluntary healthy participants were recruited through advertisements. Volunteers had to have experience of hangover and/or headache. The hangover study was randomized, double-blind and placebo-controlled. Nineteen males randomly swallowed placebo and L-cysteine tablets. The alcohol dose was 1.5 g/kg, which was consumed during 3 h.ResultsThe primary results based on correlational analysis showed that L-cysteine prevents or alleviates hangover, nausea, headache, stress and anxiety. For hangover, nausea and headache the results were apparent with the L-cysteine dose of 1200 mg and for stress and anxiety already with the dose of 600 mg.ConclusionsL-cysteine would reduce the need of drinking the next day with no or less hangover symptoms: nausea, headache, stress and anxiety. Altogether, these effects of L-cysteine are unique and seem to have a future in preventing or alleviating these harmful symptoms as well as reducing the risk of alcohol addiction.
Databáze: OpenAIRE