Serum S100B in elderly patients with and without delirium
| Autor: | Sophia E. de Rooij, Johanna C. Korevaar, Johannes M.G. Bonfrer, Aeilko H. Zwinderman, Catharina M. Korse, Barbara C. van Munster |
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| Přispěvatelé: | Geriatrics, APH - Amsterdam Public Health, Epidemiology and Data Science, ANS - Amsterdam Neuroscience, Other Research |
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Brain damage Disease behavioral disciplines and activities Central nervous system disease Rating scale Organic mental disorders Internal medicine mental disorders medicine Humans Dementia Aged Aged 80 and over Psychiatric Status Rating Scales S100 Proteins Age Factors Delirium Cognition medicine.disease nervous system diseases Surgery Psychiatry and Mental health Female Geriatrics and Gerontology medicine.symptom Cognition Disorders Psychology Biomarkers |
| Zdroj: | International journal of geriatric psychiatry, 25(3), 234-239. John Wiley and Sons Ltd |
| ISSN: | 1099-1166 0885-6230 |
| Popis: | Objective: Elevation of S100B has been shown after various neurologic diseases with cognitive dysfunction. The aim of this study was to compare the serum level of S100B of patients with and without delirium and investigate the possible associations with different subtypes of delirium. Methods: Acutely admitted medical patients aged 65 years or more were included from 2005 through 2008. Delirium was diagnosed by Confusion Assessment Method, delirium subtype by Delirium Symptom Interview and preexistent global cognitive function by the 'Informant Questionnaire on Cognitive Decline-short form'. S100B levels were determined in serum by electrochemiluminescence immunoassay. Results: Samples of 412 patients were included, 91 during delirium, 35 after delirium and 286 of patients without delirium. Patients with delirium (31%) were significantly older, 81.5 versus 76.6 years (p |
| Databáze: | OpenAIRE |
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