Primary Leiomyosarcoma in the Heart of a Guinea Pig
| Autor: | M.B. Wernick, D. D. Wiederkehr, B.R. Vogler, E. Vetsch, Titus Sydler |
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| Přispěvatelé: | University of Zurich, Wiederkehr, D D |
| Rok vydání: | 2012 |
| Předmět: |
Leiomyosarcoma
Pathology medicine.medical_specialty 10253 Department of Small Animals 3400 General Veterinary Guinea Pigs 10184 Institute of Veterinary Pathology Lumen (anatomy) Vimentin Ventricular Septum Biology Pathology and Forensic Medicine Heart Neoplasms Guinea pig Biomarkers Tumor medicine Animals Myocyte Cardiac Leiomyosarcoma General Veterinary Anatomy medicine.disease Immunohistochemistry Actins 2734 Pathology and Forensic Medicine body regions Primary Leiomyosarcoma biology.protein 570 Life sciences biology Female |
| DOI: | 10.5167/uzh-66335 |
| Popis: | Leiomyosarcoma was diagnosed in the heart of a 3-year-old female guinea pig. Neoplastic tissue was located in the ventricular septum extending into the right ventricular lumen, but was not obvious grossly. Microscopically, the mass was nodular and infiltrative and was composed of streams and bundles of spindle cells. Immunohistochemically, the neoplastic cells expressed vimentin and α-smooth muscle actin. There was no cross striation of the muscle cells. This is the first report of cardiac leiomyosarcoma in a guinea pig. |
| Databáze: | OpenAIRE |
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