CDPKs and 14-3-3 Proteins: Emerging Duo in Signaling
| Autor: | Patrice Thuleau, Christian Mazars, Valérie Cotelle, Mélanie Ormancey |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine Kinase Plant Science Biology Bioinformatics 01 natural sciences Cell biology Protein–protein interaction 03 medical and health sciences Plant development 030104 developmental biology 14-3-3 Proteins Gene Expression Regulation Plant Protein phosphorylation Signal transduction Gene Protein Kinases Intracellular 010606 plant biology & botany Calcium signaling Plant Proteins Signal Transduction |
| Zdroj: | Trends in plant science. 22(3) |
| ISSN: | 1878-4372 |
| Popis: | Calcium-dependent protein kinases (CDPKs) are Ca2+-sensors that play pivotal roles in plant development and stress responses. They have the unique ability to directly translate intracellular Ca2+ signals into reversible phosphorylation events of diverse substrates which can mediate interactions with 14-3-3 proteins to modulate protein functions. Recent studies have revealed roles for the coordinated action of CDPKs and 14-3-3s in regulating diverse aspects of plant biology including metabolism, development, and stress responses. We review here the underlying interaction and cross-regulation of the two signaling proteins, and we discuss how this insight has led to the emerging concept of CDPK/14-3-3 signaling modules that could contribute to response specificity. |
| Databáze: | OpenAIRE |
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