Diagrama de flujo inmunohistoquímico para la diferenciación entre adenocarcinomas primarios y tumores metastásicos extraginecológicos más frecuentes en el ovario
| Autor: | Mauricio Cuello F, Rodrigo Chuaqui F, Yumay Pires N, Leonardo Andrade M |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Pathology
medicine.medical_specialty endocrine system diseases biology business.industry Neoplasm metastasis Ovary General Medicine Gastrointestinal system Ovarin neoplasms Immunohistochemistry digestive system diseases medicine.anatomical_structure Flow chart biology.protein Medicine Antibody Differential diagnosis business Pathological Immunostaining |
| Zdroj: | Revista médica de Chile v.130 n.11 2002 SciELO Chile CONICYT Chile instacron:CONICYT |
| ISSN: | 0034-9887 |
| Popis: | Background: The pathological differential diagnosis between primary and metastatic ovarian malignant tumors is usually difficult, specially for tumors originating in the gastrointestinal system or breast. Aim: To define an immunohistochemical flow chart to discriminate these tumor types. Material and methods: We performed a immunostaining analysis using a panel of six antibodies (CK 7, CA 125, CEA, CK20, BRST-2 and CA 15-3) in 3 tumor groups: 11 ovarian, 14 breast and 12 colonic primary tumors and in a study group of 38 ovarian tumors whose primary origin was unknown. Results: We defined an ovarian immunohistochemical pattern (CEA-/CK20-, 45% in ovarian tumors, 0% in breast or colonic tumors, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|