Additional file 1 of Integrin β3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient

Autor: Swinehart, Brian D., Bland, Katherine M., Z. Logan Holley, Lopuch, Andrew J., Casey, Zachary O., Handwerk, Christopher J., Vidal, George S.
Rok vydání: 2020
DOI: 10.6084/m9.figshare.13467349
Popis: Additional file 1: Figure 1. (A-C) No difference in number of primary basal dendrites between C57;GFP/Cre- and Itgb3fl/fl;GFP/Cre- neurons. Figure 2. Maximum correlation coefficient (r2) values of total dendritic length versus distance z to principal axis origin, as a function of m or y0. Figure 3. Incorporating geodesic (“encephalodesic”) distance to midline slightly modifies correlations of neuronal position and dendritic complexity in C57;GFP/Cre+ and Itgb3fl/fl;GFP/Cre+ layer II/III pyramidal neurons. Figure 4. Dendritic complexity of C57;GFP/Cre+ and Itgb3fl/fl;GFP/Cre+ layer II/III pyramidal neurons in the primary somatosensory cortex. Figure 5. Somatic depth and region are not important factors when comparing dendritic morphology among targeted layer II/III neurons. Figure 6. In contrast to rostrocaudal position (Fig. 4), no correlation exists between total basal dendritic spine density and distance to principal axis origin (m = 1.56, y0 = − 350 μm) in either C57;GFP/Cre+ neurons (r2 = 0.11, p = 0.30) or Itgb3fl/fl;GFP/Cre+ neurons (r2 = 0.18, p = 0.09). Table 1. Apical morphology and high-order basal dendritic morphology of neurons are not correlated to their cortical position along a tangential gradient (distance to principal axis origin).
Databáze: OpenAIRE