Early Sensitization to Farming-Related Antigens among Young Farmers: Analysis of Risk Factors
| Autor: | Alexander Frank, Christian Prior, Markus Falk |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Hypersensitivity Immediate Male Rural Population Spirometry Allergy medicine.medical_specialty Adolescent Immunology Grammar school Atopy Radioallergosorbent Test Risk Factors Surveys and Questionnaires Prevalence medicine Humans Immunology and Allergy Family history Risk factor Skin Tests Asthma medicine.diagnostic_test business.industry Public health Age Factors General Medicine Allergens Immunoglobulin E medicine.disease Respiratory Function Tests respiratory tract diseases Austria Immunoglobulin G business |
| Zdroj: | International Archives of Allergy and Immunology. 111:182-187 |
| ISSN: | 1423-0097 1018-2438 |
| Popis: | It was the aim of this study to investigate the prevalence of and risk factors for IgE- and IgG-mediated allergy in young farmers. We investigated 147 young men attending a farming college in the Austrian Tyrol and 57 age-matched pupils at a grammar school. All individuals completed a questionnaire and had spirometry, skin prick tests, total and specific IgE analysis, and testing for precipitins against thermophilic actinomycetes and true fungi. In the farming group, a family history of atopy or asthma was reported less frequently than in the control group (p0.001) but there were no differences in the frequencies of actual respiratory symptoms. Forced expiratory volume in the first second (FEV1) was slightly lower in the farmers than in the pupils (p0.05). There was no difference in the prevalence of IgE-mediated allergy. Nine of the farmers but none of the pupils had precipitating antibodies against Faeni rectivirgula (p0.05). Overall reactivity (as defined by at least one positive finding with the skin prick test, specific IgE, or precipitins) was associated with larger farming estates, lack of a haydrying device, use of mouldy hay, and positive family history of asthma (p0.05). We conclude that in farmers, precipitin formation may occur at an early age and that even in younger age groups there is a clear relationship between allergic sensitization and occupational allergen exposure. |
| Databáze: | OpenAIRE |
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