The Prognostic Value of the iScore, the PLAN Score, and the ASTRAL Score in Acute Ischemic Stroke
| Autor: | Di Jin, Yuan Hong, Wen-Wen Sang, Huan Zhang, Shuang-Mei Yan, Wei-Ying Wang, Xu Yang |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Group based medicine.medical_specialty Time Factors 030204 cardiovascular system & hematology Risk Assessment Brain Ischemia Decision Support Techniques 03 medical and health sciences symbols.namesake Disability Evaluation 0302 clinical medicine Modified Rankin Scale Predictive Value of Tests Risk Factors Internal medicine medicine Humans In patient Acute ischemic stroke Prognostic models Aged Aged 80 and over Framingham Risk Score Receiver operating characteristic business.industry Rehabilitation Middle Aged Prognosis Pearson product-moment correlation coefficient Stroke ROC Curve Area Under Curve symbols Physical therapy Cardiology Surgery Female Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 26(6) |
| ISSN: | 1532-8511 |
| Popis: | Background Disability and mortality represent the most relevant clinical outcomes after acute ischemic stroke. Recently, a number of prognostic models of acute ischemic stroke have been developed, but they have not been extensively validated. In this study, we evaluated the ability of 3 prognostic models including the iScore, the PLAN score, and the ASTRAL score in predicting clinical poor outcomes or mortality at 6 months in patients with acute ischemic stroke. Methods A total of 323 patients were divided into a good-prognosis group and a poor-prognosis group based on the modified Rankin Scale. Model discrimination was quantified by calculating the area under the receiver operating characteristic (ROC) curve, and calibration was assessed by Hosmer–Lemeshow goodness of fit test and Pearson correlation coefficient. Results We identified 96 (29.7%) patients with poor prognosis, including 21 who were dead. All 3 models showed good ability in predicting poor prognosis and mortality in patients with acute ischemic stroke (all ROC > .70). There was no difference between these 3 models in terms of sensitivity and accuracy (all P > .05). Conclusions The results of this study suggest that the iScore, the PLAN score, and the ASTRAL score were equal in predicting 6-month poor prognosis and mortality in patients with acute ischemic stroke. Overall, there was a very high correlation between observed and expected outcomes at the risk score level. |
| Databáze: | OpenAIRE |
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