Upregulation of VDR-associated lncRNAs in Schizophrenia
| Autor: | Soudeh Ghafouri-Fard, Motahareh Seyedi, Farkhondeh Pouresmaeili, Reyhane Eghtedarian, Shahram Arsang-Jang, Mohammad Taheri |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Transcriptional Activation Oncology medicine.medical_specialty business.industry Significant difference General Medicine medicine.disease Calcitriol receptor Up-Regulation Cellular and Molecular Neuroscience Downregulation and upregulation Schizophrenia Healthy individuals Internal medicine medicine Humans Receptors Calcitriol Female RNA Long Noncoding Neurochemistry business Signal Transduction |
| Zdroj: | Journal of Molecular Neuroscience. 72:239-245 |
| ISSN: | 1559-1166 0895-8696 |
| DOI: | 10.1007/s12031-021-01901-y |
| Popis: | Vitamin D receptor (VDR) signaling has been found to contribute to the pathology of numerous neuropsychiatric diseases including schizophrenia. Notably, VDR signaling has a functional relationship with many long non-coding RNAs (lncRNAs) such as SNHG6, LINC00346 and LINC00511. We calculated expression of these lncRNAs in the venous blood of patients with schizophrenia versus healthy individuals. Expression of SNHG6 was significantly higher in cases versus controls (posterior beta = 0.552, adjusted P value |
| Databáze: | OpenAIRE |
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